Our mission is to provide homeless cats and dogs with the highest quality of life and a vital second chance to find a forever family. Every animal that comes to us is a beloved guest on their journey to a permanent, loving home.
Founded in 1975, Open Door Animal Sanctuary has grown to become the largest no-kill shelter in the greater St. Louis area and the state of Missouri. We serve our community by providing hope, help, and healing to stray, abused, neglected, and otherwise unwanted cats and dogs.
Each day, we provide dedicated love, shelter, food, and medical care to more than 350 animals. Our facility offers a largely cage-free living environment, featuring comfortable catteries like Kitty City and kennels equipped with heat, air-conditioning, and outdoor runs. We are committed to maintaining the highest standard of animal welfare 365 days a year.
We believe that adoption is a joyful partnership, which is why our experienced team works hard to match the right pet with the right situation. Whether you are looking for your first family pet or adding to your existing family, our staff is here to ensure every transition is supported with comprehensive medical and behavioral care. We also proudly offer a lifetime return policy to ensure that no animal ever loses their safety net.
Ready to meet your new best friend? We invite you to view our adoptable pets on our website or visit us in House Springs to experience our sanctuary firsthand. You can also support our mission through volunteering, fostering, or participating in our community programs as we continue to build a kinder world for animals together.