Since 1870, the Humane Society of Missouri has been dedicated to giving animals in need the second chance they deserve. We strive to create lasting, joyful relationships between people and their companion animals through our commitment to rescue, rehabilitation, and world-class care.
Founded by admirers of Henry Bergh, we have spent over 150 years working to ensure the welfare of all animals. Today, we address critical community needs by housing the Animal Cruelty Task Force, providing low-cost spay/neuter services through Operation SNIP, and offering comprehensive veterinary care at our Animal Medical Centers of Mid-America.
As the largest animal shelter in Missouri, we take pride in maintaining a safe and caring environment for the thousands of pets we serve annually. Whether an animal is in our care at our Macklind Avenue headquarters, our Best Buddy Pet Center, or our Longmeadow Rescue Ranch, they receive dedicated attention and medical support. Our foster program further ensures that animals receive essential socialization and love in a home environment while they await their forever families.
We believe that adopting a pet is the beginning of a beautiful, life-changing partnership. Our team works to evaluate the health and temperament of every animal to ensure a thoughtful match that supports both your lifestyle and the animal’s needs. We encourage you to take the time to get to know our residents, as this bond will enrich your life for years to come.
Are you ready to meet your new best friend? We invite you to visit our adoption centers, explore our current adoptable pets, or learn about our many volunteer and educational opportunities. Join us in our mission to protect and cherish the animals who share our world.